Table 2.
Differential analysis of PET texture between the young and elderly rhesus macaque groups
| Organ | Radiomics Feature(RF) | Young | Elderly | P_value | Analysis |
|---|---|---|---|---|---|
| Brain | SHAPE_Sphericity[onlyFor3DROI] | 0.707 ± 0.010 | 0.735 ± 0.012 | 0.006 | LSD |
| R-Fat | CONVENTIONAL_TLG(mL)[onlyForPETorNM] | 1.025 ± 0.613 | 2.408 ± 0.817 | 0.018 | LSD |
| DISCRETIZED_TLG(mL)[onlyForPETorNM] | 3.217(2.032,6.155) | 9.213(7.095,10.911) | 0.018 | M-W U | |
| SHAPE_Volume(mL) | 1.325(0.97,1.669) | 2.778(2.387,3.245) | 0.006 | M-W U | |
| SHAPE_Volume(vx) | 166(121,209) | 348(299,407) | 0.006 | M-W U | |
| SHAPE_Sphericity[onlyFor3DROI]) | 0.46(0.458,0.549) | 0.415(0.402,0.442) | 0.028 | M-W U | |
| SHAPE_Surface(mm2)[onlyFor3DROI] | 1194 ± 317 | 2346 ± 468 | 0 | LSD | |
| GLRLM_RLNU | 85(67,102) | 170(128,200) | 0.018 | M-W U | |
| NGLDM_Coarseness | 0.053 ± 0.014 | 0.028 ± 0.007 | 0.01 | LSD | |
| GLZLM_GLNU | 3.364(2.929,4) | 4.776(4.498,5.058) | 0.018 | M-W U | |
| GLCM_Correlation | 0.431 ± 0.143 | 0.596 ± 0.141 | 0.023 | LSD | |
| L-Fat | CONVENTIONAL_TLG(mL)[onlyForPETorNM] | 1.066(0.607,1.643) | 2.462(1.927,2.927) | 0.018 | M-W U |
| DISCRETIZED_TLG(mL)[onlyForPETorNM] | 4.064(2.431,6.083) | 9.349(7.303,11.129) | 0.018 | M-W U | |
| SHAPE_Volume(mL) | 1.289 ± 0.322 | 3.048 ± 0.832 | 0.006 | LSD | |
| SHAPE_Volume(vx) | 161 ± 40 | 382 ± 104 | 0.045 | LSD | |
| Thyroid | CONVENTIONAL_SUVbwQ2 | 0.588(0.0.535,0.673) | 0.901(0.683,0.995) | 0.018 | M-W U |
| R-Lung | CONVENTIONAL_TLG(mL)[onlyForPETorNM] | 50(36,59) | 69(66,91) | 0.006 | M-W U |
| DISCRETIZED_TLG(mL)[onlyForPETorNM] | 229(155,258) | 294(289,368) | 0.006 | M-W U | |
| SHAPE_Surface(mm2)[onlyFor3DROI] | 21,630 ± 6141 | 27,464 ± 2944 | 0.023 | LSD | |
| L-Lung | SHAPE_Volume(mL) | 109(106,139) | 172(155,186) | 0.017 | M-W U |
| SHAPE_Volume(vx) | 2501(2443,3196) | 3966(3564,4283) | 0.017 | M-W U | |
| SHAPE_Surface(mm2)[onlyFor3DROI] | 21,456 ± 2862 | 27,197 ± 2295 | 0.011 | LSD | |
| SHAPE_Compacity[onlyFor3DROI] | 5.55 ± 0.532 | 6.305 ± 0.432 | 0.028 | LSD | |
| GLRLM_GLNU | 436(390,481) | 580(484,622) | 0.018 | M-W U | |
| GLZLM_LZHGE | 85,839(51603,211465) | 345,988(176262,468263) | 0.045 | M-W U | |
| NGLDM_Busyness | 14.147 ± 7.690 | 24.213 ± 10.298 | 0.041 | LSD | |
| Stomach | CONVENTIONAL_SUVbwKurtosis | 2.224 ± 0.636 | 3.263 ± 0.769 | 0.041 | LSD |
| CONVENTIONAL_SUVbwExcessKurtosis | -0.776 ± 0.636 | 0.263 ± 0.769 | 0.041 | LSD | |
| SHAPE_Volume(mL) | 0.391(0.283,2.021) | 2.347(2.032,3.673) | 0.045 | M-W U | |
| L-Kidney | GLRLM_RLNU | 111(65,167) | 194(157,362) | 0.045 | M-W U |
| L4 | GLZLM_GLNU | 2.137 ± 0.595 | 4.056 ± 1.135 | 0.006 | LSD |
| Thymus | > 0.05 | ||||
| Aorta | > 0.05 | ||||
| Left Ventricular | > 0.05 | ||||
| Liver | > 0.05 | ||||
| Pancreas | > 0.05 | ||||
| R-Kidney | > 0.05 | ||||
| Spleen | > 0.05 |