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. 2025;26(6):2215–2223. doi: 10.31557/APJCP.2025.26.6.2215

Table 1.

General Characteristics of the Studies Included in the Final Analysis

Study
(reference)
Country Year enrolled Follow-up time Population (gender, age) Number of cases Outcome (ever use/ current use) Definition of exposure OR/RR (95% CI) Adjusted variables
2016 Bold [17] US 2013 6 months 340 ever e-cig users (12-17 years, 161 females and 179 males) 170 current use of e-cig friends use e-cig (Yes vs No) 1.36 (0.78-2.38) school type, sex, race, traditional cigarette smoking status, other tobacco use
2018 Agarwal [18] US 2014 1 year 2110 never e-cig users (18-29 years, 1401 females and 709 males) 329 ever use of e-cig number of close friends using e-cig (scored on a scale from 0 [none] to 4 [all]) 1.32 (1.11-1.57) age, gender, race/ethnicity, school enrollment, number of other tobacco products used
2018 Urman [19] US 2014 1.5 years 1164 never e-cig users (median age=17.3 years) 326 ever use of e-cig number of friends using e-cig (1 or 2 vs 0) 1.95 (1.26-3.02) gender, ethnicity, parental education, community of residence, ever use of cigarettes, hookah or cigars
(3 or 4 vs 0) 4.08 (1.96-8.49) gender, ethnicity, parental education, community of residence, ever use of cigarettes, hookah or cigars
2018 East [20] US 2016 6 months 1020 never e-cig users (11-18 years, 552 females and 468 males) NA ever use of e-cig Some friend using e-cig (Yes vs No) 3.03 (1.63-5.64) Age, gender, school performance, problem behavior, monthly alcohol use, smoking susceptibility, e-cig susceptibility, some friends smoke, some friends use e-cigarettes, at least one parent smokes, at least one parent uses e-cigarettes, sibling(s) smoke, sibling(s) use e-cigarettes, public approve of smoking, and public approve of e-cigarettes
2019 Loukas (youth) [21] US 2014 2.5 years 2288 never e-cig users and 359 cases (12-17 years, about 50% were females) 359 ever use of e-cig A close peer using e-cig (scored on a scale from 1 [none] to 5 [all]) 1.51 (1.14-1.99) sex, race, ethnicity, current other tobacco use, sensation seeking, recall of exposure to e-cig marketing
2019 Loukas (young adults) [21] US 2014 2.5 years 2423 never e-cig users and 611 cases (18-29 years, 67% were females) 611 ever use of JUUL e-cig A close peer using e-cig (scored on a scale from 1 [none] to 5 [all]) 1.37 (1.21-1.56) sex, race, ethnicity, age, college type, current other tobacco use, sensation seeking, recall of exposure to e-cig marketing
2020 Vallone [22] US 2018 1 year 6165 never e-cig users (15-34 years) NA ever use of JUUL e-cig
current use of e-cig
number of 4 closest friends using e-cig (scored on a scale from 0 [none] to 4 [all])
number of 4 closest friends using e-cig (scored on a scale from 0 [none] to 4 [all])
1.84 (1.59-2.12)
2.53 (2.05-3.11)
age group, sex, race/ethnicity, perceived financial situation, region, sexual orientation
age group, sex, race/ethnicity, perceived financial situation, region, sexual orientation
2021 Obinwa [23] US (TATAMS) 2014 3 years 3733 participants (11-15 years) NA current use of e-cig number of close friends using e-cig (a few – all vs. none) 4.29 (2.89-6.38) age, sex, and race/ ethnicity), socioeconomic class, academic performance, positive affect, sensation seeking, family member use of e-cig, social acceptability, social norm, recall of advertising for e-cig at stores, recall of social media tobacco promotion, and other substance use
2021 North [24] US 2018 1 year 3543 participants (21-34 years, 66% were females) 238 current use of pod-vape number of close friends using e-cig (scored on a scale from 0 [none] to 4 [all]) 1.32 (1.11-1.58) sex, age group, race/ethnicity, current e-cig use, current cigarette smoking, social norms, and risk perceptions
2022 Ahmad [25] Canada 2018 1 year 668 participants (16-25 years, 251 females and 417 males) 396 current use of pod-type e-cig in the last 6 months Proportion of friends using e-cig (many vs. none/some) 2.15 (1.37-3.34) age group, sex, province/territory, sensation seeking, vaping-related characteristics, polysubstance use, exposure to advertisements, and sensation seeking
2022 Wang [26] US 2016 1 year 8560 never e-cig users (12-17 years) 2393 ever use of e-cig number of best friends using e-cig (a few vs none) 2.69 (2.27-3.18) sex, age, race and ethnicity, highest parental education, severity of internalizing and externalizing mental health problems, perception of harm from e-cigarette use, current cigarette smoking status, and current use of other tobacco products
number of best friends using e-cig (some vs none) 3.69 (2.91-4.68)
number of best friends using e-cig (most vs none) 4.56 (3.14-6.63)
number of best friends using e-cig (all vs none) 4.08 (1.44-11.59)
1049 current use of e-cig number of best friends using e-cig (a few vs none) 2.69 (2.27-3.18)
number of best friends using e-cig (some vs none) 3.69 (2.91-4.68)
number of best friends using e-cig (most vs none) 4.56 (3.14-6.63)
number of best friends using e-cig (all vs none) 4.08 (1.44-11.59)