Table 4.
Correlation between Exon 5 Pathogenic Variants and Clinical Characteristics of TNBC
| Total (n=69) |
Patients without pathogenic variants |
Patients with pathogenic variants (n=17) |
p value | |
|---|---|---|---|---|
| Characteristics | ||||
| Age (years) | ||||
| ≥50 | 40 | 33 | 7 | 0.10 |
| <50 | 29 | 19 | 10 | |
| Tumor size | ||||
| >2cm | 58 | 41 | 17 | 0.053 |
| ≤2cm | 11 | 11 | 0 | |
| Tumor grade | ||||
| II | 34 | 24 | 10 | 0.364 |
| III | 35 | 28 | 7 | |
| Histology | ||||
| Infiltrating ductal carcinoma | 67 | 51 | 16 | 0.435 |
| Infiltrating lobular carcinoma | 2 | 1 | 1 | |
| Lymph node status | ||||
| Positive | 24 | 19 | 5 | 0.70 |
| Negative | 12 | 8 | 4 | |
| Missed | 33 | 25 | 8 | |