Table 3.
The Influence of Linagliptin -Ciprofloxacin Combination on the Viability of HeLa Cancer Cells at 24 and 72 hours
| Concentration (µg/ml) | Inhibition of cellular proliferation (mean ± SE a) | P- value | |
|---|---|---|---|
| 24 hr. | 72 hr. | ||
| 0.1 | D 7.00±2.000 | D 14.00±4.000 | 0.053 |
| 1 | C 19.00±2.000 | CD 23.00±3.000 | 0.127 |
| 10 | C 21.00±1.000 | C 29.00±4.000 | 0.028* |
| 100 | B 34.00±4.000 | B 44.00±4.000 | 0.038* |
| 1000 | A 47.00±3.000 | A 62.00±2.000 | 0.002* |
| b LSD value | 9.48 | 12.7 | |
| IC 50 | 1060.4 µg/ml | 640.6 µg/ml | |
a, standard error; b, least significant difference; statistically significant differences are shown by variations in capital letters within the same column; *, significant at (P<0.05)