Table 4.
The Influence of Linagliptin -Ciprofloxacin Combination on the Viability of HFF Cell Line at 24 and 72 hours
| Concentration (µg/ml) | Inhibition of cellular proliferation (mean ± SE a) | P- value | |
|---|---|---|---|
| 24 hr. | 72 hr. | ||
| 0.1 | B 0.00±.000 | C 0.00±.000 | N.S |
| 1 | B 0.00±.000 | C 2.00±1.000 | 0.026 |
| 10 | A 1.00±1.000 | BC 5.00±2.000 | 0.036 |
| 100 | A 4.00±2.000 | AB 10.00±2.000 | 0.021 |
| 1000 | A 7.00±3.000 | A 15.00±2.000 | 0.018 |
| b LSD value | 6.08 | 5.86 | |
| IC 50 | 7900.1 µg/ml | 3949 µg/ml | |
a, standard error; b, least significant difference; statistically significant differences are shown by variations in capital letters within the same column; *, significant at (P<0.05)