Table 5.
Comparison of the 24-hour Growth Inhibition of Linagliptin -Ciprofloxacin Combination between Hela and HFF Cell Lines
| Concentration (µg/ml) | Inhibition of cellular proliferation (mean ± SE a) | P- value | |
|---|---|---|---|
| Hela | HDF | ||
| 0.1 | 7.00±2.000 | 0.00±.000 | 0.004* |
| 1 | 19.00±2.000 | 0.00±.000 | 0.0001* |
| 10 | 21.00±1.000 | 1.00±1.000 | 0.0001* |
| 100 | 34.00±4.000 | 4.00±2.000 | 0.0001* |
| 1000 | 47.00±3.000 | 7.00±3.000 | 0.0001* |
| b LSD value | 9.48 | 6.08 | |
| IC 50 | 1060.4 µg/ml | 7900.1 µg/ml | |
a, standard error; b, least significant difference; statistically significant differences are shown by variations in capital letters within the same column; *, significant at (P<0.05)