Table 3. Associations between echocardiography and 99mTc-PYP scintigraphy parameters.
| Variable | Group | Positive PYP* (95% CI) | P value | H/CL ratio (95% CI) | P value |
|---|---|---|---|---|---|
| LV mass | ATTRwt | 60.96 (−35.68 to 157.59) | 0.210 | 71.19 (18.94 to 123.43) | 0.009 |
| ATTRm | 111.21 (30.51 to 191.91) | 0.009 | 134.52 (63.90 to 205.13) | 0.001 | |
| IVSd | ATTRwt | 0.339 (0.028 to 0.650) | 0.034 | 1.95 (1.26 to 2.63) | 0.001 |
| ATTRm | 0.48 (0.18 to 0.77) | 0.003 | 0.46 (0.18 to 0.73) | 0.002 | |
| LV Mass Index | ATTRwt | 29.69 (−14.53 to 73.91) | 0.200 | 36.11 (14.33 to 57.89) | 0.002 |
| ATTRm | 64.77 (26.92 to 102.62) | 0.002 | 67.81 (37.33 to 98.29) | 0.001 | |
| LVPWd | ATTRwt | 0.27 (−0.04 to 0.58) | 0.100 | 0.34 (0.18 to 0.50) | 0.001 |
| ATTRm | 0.49 (0.23 to 0.75) | 0.001 | 0.49 (0.25 to 0.73) | 0.001 |
Positive PYP includes results yielding grade 2 or 3.
ATTRm, hereditary transthyretin amyloidosis; ATTRwt, wild type transthyretin amyloidosis; H/CL, heart-to-contralateral lung (ratio); IVSd, interventricular septal thickness at end-diastole; LV, left ventricular; LVPWd, left ventricular posterior wall thickness at end-diastole; 99mTc-PYP, technetium-99m pyrophosphate; PYP, pyrophosphate.