Skip to main content
. 2025 Jul 28;15(16):8509–8530. doi: 10.7150/thno.118901

Figure 4.

Figure 4

In vitro and in vivo biocompatibility. (A) Relative cell viability of L929 fibroblasts co-cultured with GM-Lap@PDA microspheres extracts for 24 h (the red asterisks represent the comparison of the experimental group with the control group at the same concentration, n = 5, *p < 0.05, **p < 0.01, and ***p < 0.001). (B) Live/dead cell fluorescence images (n = 4). (C) Schematic diagram of the subcutaneous implantation experiments. (D) The digital photographs of the subcutaneous implantation area at different time points (the blue arrows indicate the degraded residual gels or sponges) (n = 6). (E) Representative images of H&E staining and Masson staining of tissue in the subcutaneous implantation area at 14 days postoperatively (* indicates the degraded residual material).