Table 2. HR (95% CI) of MACEs, all-cause death, all-cause readmission and unplanned readmission according to aAIP in the three models.
| Endpoints | Event, n (%) | Model 1 | Model 2 | Model 3 | |||
|---|---|---|---|---|---|---|---|
| HR (95% CI) | P value | HR (95% CI) | P value | HR (95% CI) | P value | ||
| MACEs | |||||||
| Continuous variable | 68 (20.36) | 8.06 (4.695 to 13.848) |
＜0.001 | 13.507 (7.427 to 24.564) |
<0.001 | 38.169 (18.040 to 80.759) |
＜0.001 |
| aAIP quartile | |||||||
| Q1 | 3 (0.90) | Ref | Ref | Ref | Ref | Ref | Ref |
| Q2 | 2 (0.60) | 0.666 (0.111 to 3.985) |
0.656 | 0.746 (0.124 to 4.474) |
0.748 | 1.089 (0.174 to 6.840) |
0.927 |
| Q3 | 23 (6.89) | 8.837 (2.652 to 29.445) |
＜0.001 | 10.844 (3.231 to 36.393) |
<0.001 | 17.676 (4.837 to 64.591) |
＜0.001 |
| Q4 | 40 (11.98) | 16.923 (5.229 to 54.773） |
＜0.001 | 26.186 (7.965 to 86.094) |
＜0.001 | 47.077 (13.069 to 169.581) |
＜0.001 |
| P for trend | ＜0.001 | ＜0.001 | ＜0.001 | ||||
| All-cause death | |||||||
| Continuous variable | 10 (2.99) | 5.273 (1.186 to 23.444) |
0.029 | 18.355 (3.003 to 62.210) |
0.002 | 36.951 (4.015 to 140.044) |
0.001 |
| aAIP quartile | |||||||
| Q1 | 1 (0.00) | Ref | Ref | Ref | Ref | Ref | Ref |
| Q2 | 1 (0.00) | 0.980 (0.061 to 15.677) |
0.989 | 1.369 (0.084 to 22.261) |
0.825 | 1.365 (0.083 to 22.489) |
0.828 |
| Q3 | 3 (0.90) | 3.219 (0.335 to 30.964) |
0.311 | 4.736 (0.477 to 46.979) |
0.184 | 5.894 (0.551 to 63.061) |
0.142 |
| Q4 | 5 (1.49) | 5.647 (0.658 to 48.433) |
0.114 | 12.720 (1.389 to 76.436) |
0.024 | 16.181 (1.662 to 117.495) |
0.016 |
| P for trend | 0.037 | 0.007 | 0.005 | ||||
| All-cause readmission | |||||||
| Continuous variable | 79 (23.65) | 3.745 (2.158 to 6.500) |
<0.001 | 4.220 (2.346 to 7.593) |
<0.001 | 4.977 (2.621 to 9.454) |
<0.001 |
| aAIP quartile | |||||||
| Q1 | 12 (3.59) | Ref | Ref | Ref | Ref | Ref | Ref |
| Q2 | 11 (3.29) | 0.912 (0.402 to 2.067) |
0.825 | 0.913 (0.402 to 2.075) |
0.828 | 1.025 (0.439 to 2.393) |
0.955 |
| Q3 | 20 (5.99) | 1.919 (0.938 to 3.928) |
0.074 | 1.973 (0.957 to 4.069) |
0.066 | 2.242 (1.043 to 4.818) |
0.039 |
| Q4 | 36 (10.78) | 3.774 (1.960 to 7.267) |
<0.001 | 4.461 (2.264 to 8.789) |
<0.001 | 5.378 (2.557 to 11.314) |
<0.001 |
| P for trend | <0.001 | <0.001 | <0.001 | ||||
| Unplanned readmission | |||||||
| Continuous variable | 68 (20.36) | 4.737 (2.669 to 8.406) |
<0.001 | 5.555 (3.006 to 10.264) |
<0.001 | 6.646 (3.399 to 12.994) |
<0.001 |
| aAIP quartile | |||||||
| Q1 | 9 (2.69) | Ref | Ref | Ref | Ref | Ref | Ref |
| Q2 | 8 (2.39) | 0.888 (0.343 to 2.303) |
0.807 | 0.895 (0.344 to 2.327) |
0.820 | 1.081 (0.402 to 2.907) |
0.877 |
| Q3 | 18 (5.39) | 2.329 (1.045 to 5.186) |
0.039 | 2.439 (1.085 to 5.480) |
0.031 | 2.945 (1.246 to 6.960) |
0.014 |
| Q4 | 33 (9.88) | 4.732 (2.260 to 9.910) |
<0.001 | 5.706 (2.660 to 12.238) |
<0.001 | 7.281 (3.146 to 16.848) |
<0.001 |
| P for trend | <0.001 | <0.001 | <0.001 | ||||
Model 1 represented the unadjusted data.
Model 2 adjusted for age, sex and BMI.
Model 3 adjusted for age, sex, BMI, Ccr, current drinking, hypertension, type 2 diabetes and LDL-C.
aAIP, adjusted atherogenic index of plasma; BMI, body mass index; Ccr, creatinine clearance; LDL-C, low-density lipoprotein cholesterol; MACE, major adverse cardiovascular event.