Table 7.
Simulation results for discovering dose-response relationship under partial compliance with imprecise laboratory tests (10% false positive and negative rates). We consider the estimating procedure, described in Section 4.3, with or without covariate adjustment and report the bias, probability of rejecting the null hypothesis (PoR), and the coverage probability of nominal 0.95 confidence intervals based on Normal approximations (CP)
| Covariate adjustment | Bias | PoR | CP | |
|---|---|---|---|---|
| log(1) = 0 | No | 0.00 | 0.05 | 0.95 |
| Yes | 0.00 | 0.04 | 0.96 | |
| log(0.6) = −0.51 | No | 0.16 | 0.10 | 0.94 |
| Yes | 0.16 | 0.15 | 0.93 | |
| log(0.2) = −1.61 | No | 0.62 | 0.52 | 0.75 |
| Yes | 0.63 | 0.90 | 0.47 |