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. 2025 Jul 28;21(11):4979–4996. doi: 10.7150/ijbs.111449

Table 2.

Signaling pathways through the identification of differentially expressed genes based on RNA sequencing

Term Count Count% p-value FDR Fold Enrichment
hsa05200: Pathways in cancer 48 4.968944 1.45E-04 0.007682 1.75848474
hsa05165: Human papillomavirus infection 37 3.830228 1.35E-05 0.001788 2.17453107
hsa04151: PI3K-Akt signaling pathway 31 3.20911 0.004453535 0.051312 1.70353209
hsa04010: MAPK signaling pathway 28 2.898551 0.002269414 0.037587 1.85268928
hsa05169: Epstein-Barr virus infection 25 2.587992 9.75E-05 0.007682 2.40757889
hsa04015: Rap1 signaling pathway 25 2.587992 1.79E-04 0.007905 2.3158616
hsa05132: Salmonella infection 25 2.587992 0.002088988 0.037587 1.95313629
hsa04060: Cytokine-cytokine receptor interaction 25 2.587992 0.01660764 0.106027 1.64857944
hsa04080: Neuroactive ligand-receptor interaction 25 2.587992 0.095004708 0.286094 1.37770803
hsa05163: Human cytomegalovirus infection 23 2.380952 0.002635446 0.039046 1.98855316
hsa05131: Shigellosis 23 2.380952 0.00798429 0.070528 1.81143506
hsa05170: Human immunodeficiency virus 1 infection 22 2.277433 0.002799537 0.039046 2.01873218
hsa04390: Hippo signaling pathway 21 2.173913 1.43E-04 0.007682 2.60202539
hsa04360: Axon guidance 21 2.173913 0.001006093 0.029624 2.24460432
hsa05417: Lipid and atherosclerosis 21 2.173913 0.007047123 0.065855 1.90008365