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. 2025 Jul 25;21(11):4816–4833. doi: 10.7150/ijbs.107763

Table 3.

Clinical and pathological characteristics of 119 patients with breast cancer in the present validation cohort

Clinical and pathological characteristics Tis/Stage I (%) N=34 Stage II (%) N=22 Stage III (%) N=20 Stage IV (%) N=43 P value
Age (years) 0.870
< 50 17 (50.0) 9 (40.9) 10 (50.0) 22 (51.2)
≥ 50 17 (50.0) 13 (59.1) 10 (50.0) 21 (48.8)
T < 0.001
Tis 5 (14.7) 0 0 0
T1 29 (85.3) 4 (18.2) 0 10 (23.3)
T2 0 17 (77.3) 1 (5.0) 25 (58.1)
T3 0 1 (4.5) 13 (65.0) 3 (7)
T4 0 0 6 (30.0) 5 (11.6)
N < 0.001
Negative 34 (100.0) 2 (9.1) 1 (5.0) 12 (27.9)
Positive 0 20 (90.9) 19 (95.0) 31 (72.1)
M < 0.001
Negative 34 (100.0) 22 (100.0) 20(100.0) 0
Positive 0 0 0 43(100.0)
ER < 0.001
Negative 6 (17.6) 5 (22.7) 8 (40.0) 33 (76.7)
Positive 28 (82.4) 17 (77.3) 12 (60.0) 10 (23.3)
PR < 0.001
Negative 6 (17.6) 8 (36.4) 9 (45.0) 35 (81.4)
Positive 28 (82.4) 14 (63.6) 11 (55.0) 8 (18.6)
HER2 0.002
Negative 31 (91.2) 13 (59.1) 15 (75.0) 40 (93.0)
Positive 3 (8.8) 9 (40.9) 5 (25.0) 3 (7.0)
Ki67 0.002
≤ 20% 16 (47.1) 3 (13.6) 4 (20.0) 5 (11.6)
> 20% 18 (52.9) 19 (86.4) 16 (80.0) 38 (88.4)
Immunohistochemical type < 0.001
Luminal 27 (79.4) 10 (45.5) 10 (50.0) 9 (20.9)
HER2 positive 3 (8.8) 9 (40.9) 5 (25.0) 3 (7.0)
TNBC 4 (11.8) 3 (13.6) 5 (25.0) 31 (72.1)