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. 2025 Jul 25;21(11):4816–4833. doi: 10.7150/ijbs.107763

Table 4.

Baseline clinical and pathological information of the JCAD high- and low-expression groups in the present study cohort

Clinical and pathological characteristics Total (%)
N=111
JCAD expression P value
Low (%)
N=55
High (%)
N=56
Age (years, Inline graphic±s) 50.1±9.1 52.5±9.4 0.159
Age (years) 0.218
< 50 48 (43.2) 27 (49.1) 21 (37.5)
≥ 50 63 (56.8) 28 (50.9) 35 (62.5)
T 0.380
T1 32 (28.8) 20 (36.4) 12 (21.4)
T2 53 (47.7) 23 (41.8) 30 (53.6)
T3 15 (13.5) 7 (12.7) 8 (14.3)
T4 11 (9.9) 5 (9.1) 6 (10.7)
N 0.552
Negative 38 (34.2) 19 (34.5) 19 (33.9)
Positive 73 (65.8) 36 (65.5) 37 (66.1)
M 0.005
M0 77 (69.4) 45 (81.8) 32 (57.1)
M1 34 (30.6) 10 (18.2) 24 (42.9)
Stage 0.037
I 26 (23.4) 15 (27.3) 11 (19.6)
II 36 (32.4) 20 (36.4) 16 (28.6)
III 15 (13.5) 10 (18.2) 5 (8.9)
IV 34 (30.6) 10 (18.2) 24 (42.9)
ER 0.509
Negative 53 (47.7) 28 (50.9) 25 (44.6)
Positive 58 (52.3) 27 (49.1) 31 (55.4)
PR 0.785
Negative 64 (57.7) 31 (56.4) 33 (58.9)
Positive 47 (42.3) 24 (43.6) 23 (41.1)
HER2 0.379
Negative 64 (57.7) 34 (61.8) 30 (53.6)
Positive 47 (42.3) 21 (38.2) 26 (46.4)
Immunohistochemical type 0.371
Luminal 58 (52.3) 27 (49.1) 31 (55.4)
HER2 positive 27 (24.3) 12 (21.8) 15 (26.8)
TNBC 26 (23.4) 16 (29.1) 10 (17.9)