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. 2025 Jul 24;16(11):3296–3313. doi: 10.7150/jca.113046

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GO and KEGG analysis of DEGs from radioresistant patients comparing with sensitive ones with lung cancer in TCGA. (A) Volcano plot of the 1,482 DEGs. The red triangles represent the significantly up-regulated genes, and the blue triangles showed the significantly down-regulated genes. (B) Heat map showed the TOP20 up-regulated and down-regulated genes respectively. (C) GO enrichment analysis of the DEGs. (D) KEGG enrichment analysis of the DEGs. (E) The venn diagram of radiotherapy resistance DEGs and lactate-related genes.