Table 4.

Evaluation of CRP (first), CRP (second), velocity of CRP and IBI in patients with preterm premature rupture of membranes for prediction of delivery in 48 h using ROC analysis

	PPV	NPV	Cutoff*	Sensitivity	Specificity	AUC	%95 CI	p value
CRP (first)	0.43	0.65	> 8.61	55%	53%	0.580	0.51–0.65	0.027
CRP (second)	0.47	0.70	> 10.08	68%	50%	0.623	0.56–0.69	0.001
Velocity of CRP	0.46	0.85	> 0.17	70%	67%	0.675	0.61–0.74	< 0.001
IBI	0.53	0.55	> 35.8	61%	50%	0.563	0.50–0.62	0.047

A p value of 0.05 indicates a significant difference and statistically significant p values are in bold

^*Cutoff values were found according to Youden index

PPV positive predictive value, NPV negative predictive value, AUC area under the curve, CI confidence interval, CRP C-reactive protein, IBI inflammatory burden index