Skip to main content
. 2025 Jun 28;312(3):979–988. doi: 10.1007/s00404-025-08089-1

Table 7.

Evaluation of CRP (first), CRP (second), velocity of CRP and IBI in patients with preterm premature rupture of membranes for prediction of delivery in 7 days using ROC analysis

PPV NPV Cutoff* Sensitivity Specificity AUC %95 CI p value
CRP (first) 0.71 0.35 7.56 58% 50% 0.57 0.50–0.65 0.045
CRP (second) 0.730
Velocity of CRP 0.630
IBI 0.79 0.32 37.3 67% 50% 0.62 0.55–0.69 0.002

A p value of 0.05 indicates a significant difference and statistically significant p values are in bold

*Cutoff values were found according to Youden index

PPV positive predictive value, NPV negative predictive value, AUC area under the curve, CI confidence interval, CRP C-reactive protein, IBI inflammatory burden index