Table 1.
General characteristics of PCOS and control groups
| Parameter | PCOS (n = 161) | Control (n = 107) | P-value |
|---|---|---|---|
| Age (years) | 24.79 ± 4.86 | 24.29 ± 4.83 | 0.410 |
| BMI (kg/m2) | 22.87 ± 4.06 | 19.91 ± 1.76 | < 0.001 |
| AMH (ng/mL) | 7.85 ± 3.24 | 3.63 ± 1.96 | < 0.001 |
| HCY (μmol/L) | 11.73 ± 3.71 | 6.90 ± 2.09 | < 0.001 |
| HOMA-IR | 2.23 ± 1.89 | 1.53 ± 0.72 | < 0.001 |
| Fasting Insulin (μIU/mL) | 9.91 ± 7.52 | 7.51 ± 3.36 | < 0.001 |
| Fasting Blood Glucose (mmol/L) | 4.91 ± 0.48 | 4.58 ± 0.35 | < 0.001 |
| CRP (mg/L) | 2.24 ± 2.73 | 1.35 ± 1.39 | 0.001 |
| Triglycerides (mmol/L) | 1.20 ± 0.75 | 0.87 ± 0.46 | < 0.001 |
| HDL (mmol/L) | 1.47 ± 0.37 | 1.73 ± 0.35 | < 0.001 |
| LDL (mmol/L) | 2.66 ± 0.73 | 2.40 ± 0.70 | 0.004 |
| Total Cholesterol (mmol/L) | 4.75 ± 0.86 | 4.47 ± 0.82 | 0.008 |
| TXNIP (ng/mL) | 0.32 ± 0.09 | 0.29 ± 0.05 | < 0.001 |
Note: P < 0.05 indicates statistical significance. Data are expressed as mean ± standard deviation
Abbreviation: BMI body mass index, AMH anti-Müllerian hormone, HCY homocysteine, HOMA-IR homeostatic model assessment of insulin resistance, FIns fasting insulin, FBG, fasting blood glucose, CRP C-reactive protein, TG triglycerides, HDL high-density lipoprotein, LDL low-density lipoprotein, TC total cholesterol, TXNIP thioredoxin-interacting protein