Table 2.
TXNIP levels and metabolic parameters in PCOS with non-IR-PCOS and IR-PCOS
| Parameter | IR-PCOS (n = 41) | Non-IR-PCOS (n = 120) | P-value |
|---|---|---|---|
| Age (years) | 24.44 ± 5.04 | 24.91 ± 4.81 | 0.595 |
| BMI (kg/m2) | 27.12 ± 3.39 | 21.41 ± 3.16 | < 0.001 |
| AMH (ng/mL) | 7.24 ± 3.19 | 8.06 ± 3.24 | 0.159 |
| HCY (µmol/L) | 11.62 ± 3.05 | 11.77 ± 3.92 | 0.820 |
| CRP (mg/L) | 3.32 ± 2.82 | 1.87 ± 2.61 | 0.003 |
| TG (mmol/L) | 1.60 ± 0.71 | 1.06 ± 0.71 | < 0.001 |
| HDL (mmol/L) | 1.24 ± 0.29 | 1.54 ± 0.36 | < 0.001 |
| LDL (mmol/L) | 2.93 ± 0.71 | 2.57 ± 0.73 | 0.007 |
| TC (mmol/L) | 4.89 ± 0.78 | 4.71 ± 0.89 | 0.250 |
| TXNIP (ng/mL) | 0.42 ± 0.10 | 0.29 ± 0.06 | < 0.001 |
Note: P < 0.05 indicates statistical significance. Data are expressed as mean ± standard deviation
Abbreviations: BMI body mass index, AMH Anti-Müllerian hormone, HCY homocysteine, CRP C-reactive protein, TG triglycerides, HDL high-density lipoprotein, LDL low-density lipoprotein, TC total cholesterol, TXNIP thioredoxin-interacting protein, IR-PCOS insulin-resistant PCOS group, Non-IR-PCOS non-insulin-resistant PCOS group