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. 2025 Jul 2;40(8):915–923. doi: 10.1007/s10654-025-01267-0

Table 1.

Basic characteristics of the nested case-control study of depression

Care Register for Health Care and Register of Primary Health Care visits
Cases (N = 23,480) Controls (N = 93,880)
N % N %
Marital status
Unmarried 17,664 75.2 70,639 75.2
Married 4285 18.2 19,526 20.8
Divorced 1442 6.1 3487 3.7
Widowed 46 0.2 122 0.1
Other 43 0.2 106 0.1
Socioeconomic group
Self-employed 650 2.8 2934 3.1
Upper-level employees 1561 6.6 9566 10.2
Lower-level employees 5804 24.7 29,295 31.2
Manual workers 3406 14.5 14,385 15.3
Students 6738 28.7 23,046 24.5
Pensioners 500 2.1 1297 1.4
Others 3227 13.7 7687 8.2
Unknown 1594 6.8 5670 6.0
Education
Upper secondary 12,071 51.4 45,454 48.4
Post-secondary non-tertiary 105 0.4 474 0.5
Short-cycle tertiary 286 1.2 1497 1.6
Bachelor 3082 13.1 16,502 17.6
Master 1150 4.9 7787 8.3
Doctoral 42 0.2 374 0.4
Missing (including, e.g., missing information on education other than of primary school level, school dropouts) 6744 28.7 21,792 23.2
Age group *
15–19 years 4296 18.3 17,168 18.3
20–24 years 6795 28.9 27,170 28.9
25–29 years 5125 21.8 20,495 21.8
30–34 years 3083 13.1 12,327 13.1
35–39 years 2052 8.7 8206 8.7
40–44 years 1338 5.7 5350 5.7
45–49 years 791 3.4 3164 3.4
Previous psychiatric hospitalizations
No 13,552 57.7 89,962 95.8
In the previous 6 months 9132 38.9 2080 2.2
6 to 24 months before 796 3.4 1838 2.0
Cancer in the previous 5 years 203 0.9 678 0.7
Chronic diseases at baseline
Hypothyroidism 197 0.8 599 0.6
Multiple sclerosis 65 0.3 195 0.2
Epilepsy 328 1.4 866 0.9
Severe psychiatric disorders 532 2.3 774 0.8
Connective tissue diseases 374 1.6 1165 1.2
Ulcerative cholitis or Chron’s disease 237 1.0 735 0.8
Diabetes mellitus 491 2.1 1142 1.2
Former HC use 11,129 47.4 47,229 50.3
Recent delivery
No 21,878 93.2 86,601 92.2
In the previous 6 months 315 1.3 1346 1.4
6 to 24 months before 1287 5.5 5933 6.3

* Matched by age

HC hormonal contraception