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. 2025 Jul 2;40(8):915–923. doi: 10.1007/s10654-025-01267-0

Table 2.

Hormonal contraception use in the nested case-control study of depression, care register for health care and register of primary health care visits. Cases, N = 23,480; controls, N = 93,880

HC use = one redeemed prescription HC use = two redeemed prescriptions
Cases Controls Cases Controls
N % N % N % N %
HC use
No HC 16,652 70.9 63,682 67.8 19,150 81.6 74,245 79.1
Current HC 6828 29.1 30,198 32.2 4330 18.4 19,635 20.9
Combined hormonal contraception 4762 20.3 22,866 24.4 3148 13.4 15,264 16.3
Ethinylestradiol containing 3608 15.4 17,505 18.6 2345 10.0 11,364 12.1
Estradiol containing 1154 4.9 5361 5.7 803 3.3 3900 4.2
Progestin-only 2066 8.8 7332 7.8 1182 5.0 4371 4.7
Combined hormonal contraceptives (ATC code)
Levonorgestrel and ethinylestradiol (G03AA07) 91 0.4 400 0.4 49 0.2 243 0.3
Desogestrel and ethinylestradiol (G03AA09) 459 2.0 2329 2.5 264 1.1 1331 1.4
Gestodene and ethinylestradiol (G03AA10) 678 2.9 3622 3.9 431 1.8 2299 2.4
Drospirenone and ethinylestradiol (G03AA12) 1747 7.4 8645 9.2 1082 4.6 5335 5.7
Norelgestromin and ethinylestradiol patch (G03AA13) 105 0.4 297 0.3 75 0.3 212 0.2
Nomegestrol and estradiol (G03AA14) 395 1.7 2165 2.3 228 1.0 1279 1.4
Dienogest and ethinylestradiol (G03AA16) 106 0.5 353 0.4 59 0.3 205 0.2
Dienogest and estradiol-valerate (G03AB08) 186 0.8 836 0.9 124 0.5 486 0.5
Etonogestrel and ethinylestradiol vaginal ring (G02BB01) 484 2.1 2052 2.2 294 1.3 1374 1.5
Progestin-only oral contraceptives
Norethisterone (G03AC01) 184 0.8 618 0.7 104 0.4 355 0.4
Levonorgestrel (G03AC03) 89 0.4 303 0.3 37 0.2 117 0.1
Desogestrel (G03AC09) 1827 7.8 6541 7.0 1022 4.4 3860 4.1
Antiandrogen and estrogen
Cyproterone and estrogen (G03HB01) 630 2.7 2684 2.9 453 1.9 2120 2.3