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. 2025 May 27;312(3):755–764. doi: 10.1007/s00404-025-08064-w

Table 3.

Basic treatment regimens for first trimester screening

Characteristics N (%)
Correction of the due date by measured crown-rump length
 No 1 (2.63)
 Always 8 (21.1)
 Depending on the distance to the originally expected date of delivery 29 (76.32)
Conducting first-trimester screening with ß-HCG and PAPP-A
 Yes 24 (63.16)
 No 4 (10.53)
 Optional 10 (26.32)
Offer of first-trimester screening without laboratory services
 Yes 14 (36.84)
 No 11 (28.95)
 Optional 13 (34.21)
Does the performance of laboratory services depend on performed risk calculation of first-trimester screening
 Yes 10 (26.32)
 No 15 (39.47)
 Optional 13 (34.21)
Performance of an amniocentesis/chorionic villus sampling autonomously
 Yes 17 (44.74)
Dependence of the decision for amniocentesis/chorionic villus sampling
 Nuchal translucency measurement / limits of nuchal translucency 20 (52.63)
 Biochemistry (ß- HCG and PAPP A) 7 (18.42)
 Combination of first-trimester screening and biochemistry 30 (78.95)
Limit value of the nuchal translucency measurement for performing amniocentesis/chorionic villus sampling
> 2.5 mm 9 (23.68)
> 3.0 mm 16 (42.11)
> 3.5 mm 7 (18.42)
 No value 4 (10.53)