Table 2.
Fetal and neonatal outcomes
| Variable | Singleton (N = 161) | First twin (N = 77) | Second twin (N = 77) | p |
|---|---|---|---|---|
| Outcome | ||||
| Livebirth | 156 (96.9%) | 75 (97.4%) | 77 (100%) | 0.728; 0.295* |
| Neonatal Death | 1 (0.6%) | 1 (1.3%) | 0 | |
| Stillbirth | 4 (2.5%) | 1 (1.3%) | 0 | |
| Arterial cord blood pH | 7.30 (0.12) | 7.31 (0.07) | 7.29 (0.11) | 0.940; 0.687* |
| Arterial cord blood pH < 7 | 0 | 1 (0.01%) | 0 | 0.106; 1* |
| Venous cord blood pH | 7.33 (0.07) | 7.35 (0.05) | 7.35 (0.03) | 0.096; 0.436* |
| Apgar test score 5` | 10 (1) | 10 (0) | 10 (1) | 0.069; 0.294* |
| Birthweight, grams ** | 2,317.2 (445.8) | 2,160.4 (480.7) | 2,538.4 (881.4) | 0.171; 0.026* |
| Birthweight, centile | 30 (58) | 30 (50.5) | 15 (33) | 0.999; 0.005* |
| Birthweight < 10th centile | 48 (30.6%) | 19 (25%) | 32 (41.6%) | 0.379; 0.097* |
| nICU admission | 28 (17.8%) | 6 (7.8%) | 10 (13.0%) | 0.041; 0.345* |
| nICU admission time, days | 15.0 (19) | 7.5 (5) | 7.0 (5) | 0.174; 0.029* |
| Neonatal complications | 47 (29.2%) | 23 (30.0%) | 21 (27.3%) | 0.890; 0.790 |
| Ventilation | 36 (22.4%) | 13 (16.9%) | 8 (10.4%) | 0.300; 0.024* |
| Intubation | 16 (9.9%) | 2 (2.6%) | 2 (2.6%) | 0.060; 0.058* |
| Intubation time, days | 2.0 (2) | 1 (66) | 3.5 (1) | 0.995; 0.659* |
| CPAP | 30 (18.6%) | 8 (10.4%) | 6 (7.8%) | 0.099; 0.029* |
| CPAP time, days | 0 (1) | 2 (4) | 1.75 (2) | 0.001; 0.012* |
| RDS | 36 (22.4%) | 12 (15.6%) | 7 (9.1%) | 0.204; 0.013* |
| Phototherapy | 29 (18.0%) | 12 (15.6%) | 16 (20.8%) | 0.602; 0.674 |
| Phototherapy, days | 2 (2) | 1 (1) | 1.5 (1) | 0.389; 0.789* |
| Intraventricular hemorrhage | 2 (1.2%) | 2 (2.6%) | 0 | 0.464; < 0.001* |
| Anemia | 7 (4.3%) | 4 (5.2%) | 2 (2.6%) | 0.790; 0.492* |
| Blood transfusion | 4 (2.5%) | 2 (2.6%) | 2 (2.6%) | 0.976; 0.982* |
| Necrotizing enterocolitis | 4 (2.5%) | 1 (1.3%) | 0 | 0.550; < 0.001* |
| Retinopathy | 6 (3.7%) | 1 (1.3%) | 0 | 0.316; < 0.001* |
| Sepsis | 5 (3.1%) | 2 (2.6%) | 3 (3.9%) | 0.812; 0.779* |
Values are median (Interquartile range) or absolute frequency (relative frequency). Statistically significant comparisons are represented in bold
nICU neonatal intensive care unit, IMV Invasive Mechanical Ventilation. RDS Respiratory Distress Syndrome. *Comparing second twin with singleton with Bonferroni correction. **Variables reported as means (standard deviation)