Table 3.

Meta-analysis of the MTR rs1805087 polymorphism and glioma risk

Comparison	Population	N	Test of association			Mode	Test of heterogeneity
			OR	95%CI	P		χ2	P	I2
G vs. A	Overall	7	0.93	0.74–1.17	0.532	Random	17.32	0.008	65.4
	Asian	1	1.14	0.73–1.77	0.572	–	–	–	–
	Caucasian	6	0.91	0.71–1.16	0.438	Random	15.92	0.007	68.6
GG vs. AA	Overall	7	0.69	0.47–1.02	0.066	Random	5.72	0.455	0
	Asian	1	0.44	0.08–2.39	0.344	–	–	–	–
	Caucasian	6	0.71	0.47–1.07	0.099	Fixed	5.41	0.368	7.6
GA vs. AA	Overall	7	0.98	0.74–1.30	0.907	Random	17.90	0.006	66.5
	Asian	1	1.48	0.85–2.58	0.165	–	–	–	–
	Caucasian	6	0.93	0.69–1.24	0.612	Random	14.55	0.012	65.6
GG vs. GA/AA	Overall	7	0.71	0.48–1.06	0.091	Fixed	4.51	0.609	0
	Asian	1	0.37	0.07–1.97	0.246	–	–	–	–
	Caucasian	6	0.74	0.50–1.11	0.151	Fixed	3.85	0.571	0
GG/GA vs. AA	Overall	7	0.96	0.72–1.27	0.758	Random	19.25	0.004	68.8
	Asian	1	1.36	0.79–2.34	0.262	–	–	–	–
	Caucasian	6	0.91	0.68–1.23	0.539	Random	16.52	0.006	69.7

OR odds ratio, CI confidence interval