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. 2025 Jul 28;16(11):3485–3496. doi: 10.7150/jca.114359

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(A) Boxplot showing ssGSEA results, indicating significantly lower DE-Anoikis scores in cancer tissues compared to normal tissues. (B) One-way Cox analysis of DE-Anoikis in the TCGA-LIHC dataset, identifying 10 genes with p < 0.05. (C) Consensus clustering heatmap of the TCGA-LIHC dataset. (D) Clinicopathological characteristics of the two molecular subtypes in the TCGA-LIHC dataset. (E) Kaplan-Meier (KM) curves illustrating overall survival (OS) prognosis of the two molecular subtypes. (F) Radar plot showing the top 10 differentially expressed genes between C1 and C2 subtypes, where red dots represent upregulated genes and green dots represent downregulated genes.