Table 1.
Baseline characteristics of AGC patient treated with PD-1 inhibitors
| Characteristics | HSP90α (Before PSM) | P value2 | HSP90α (After PSM) | P value2 | ||
|---|---|---|---|---|---|---|
| ≤82, N=511 | >82, N=791 | ≤82, N=411 | >82, N=411 | |||
| Gender | 0.724 | 0.557 | ||||
| Male | 38 (75%) | 61 (77%) | 33 (80%) | 35 (85%) | ||
| Female | 13 (25%) | 18 (23%) | 8 (20%) | 6 (15%) | ||
| Age | 0.986 | 0.594 | ||||
| ≤65 | 33 (65%) | 51 (65%) | 31 (76%) | 33 (80%) | ||
| >65 | 18 (35%) | 28 (35%) | 10 (24%) | 8 (20%) | ||
| ECOG PS | 0.679 | >0.999 | ||||
| ≤1 | 48 (94%) | 76 (96%) | 40 (98%) | 39 (95%) | ||
| ≥2 | 3 (6%) | 3 (4%) | 1 (2%) | 2 (5%) | ||
| Peritoneum metastasis | 0.483 | 0.607 | ||||
| Negative | 39 (76%) | 56 (71%) | 30 (73%) | 32 (78%) | ||
| Positive | 12 (24%) | 23 (29%) | 11 (27%) | 9 (22%) | ||
| Liver metastasis | 0.679 | 0.507 | ||||
| Negative | 29 (57%) | 42 (53%) | 23 (56%) | 20 (49%) | ||
| Positive | 22 (43%) | 37 (47%) | 18 (44%) | 21 (51%) | ||
| Lung metastasis | 0.275 | >0.999 | ||||
| Negative | 45 (88%) | 64 (81%) | 35 (85%) | 35 (85%) | ||
| Positive | 6 (12%) | 15 (19%) | 6 (15%) | 6 (15%) | ||
| Lymph node metastasis | 0.980 | 0.825 | ||||
| Negative | 24 (47%) | 37 (47%) | 19 (46%) | 20 (49%) | ||
| Positive | 27 (53%) | 42 (53%) | 22 (54%) | 21 (51%) | ||
| Metastasis sites | 0.928 | 0.432 | ||||
| ≤2 | 41 (80%) | 63 (80%) | 33 (80%) | 30 (73%) | ||
| ≥3 | 10 (20%) | 16 (20%) | 8 (20%) | 11 (27%) | ||
| Treatment lines | 0.064 | 0.775 | ||||
| ≤2 | 34 (67%) | 64 (81%) | 33 (80%) | 34 (83%) | ||
| ≥3 | 17 (33%) | 15 (19%) | 8 (20%) | 7 (17%) | ||
| Treatment types | 0.783 | 0.416 | ||||
| Chemotherapy + targeted therapy | 16 (31%) | 21 (26%) | 12 (29%) | 10 (24%) | ||
| Chemotherapy | 30 (59%) | 48 (61%) | 27 (66%) | 25 (61%) | ||
| Others | 5 (10%) | 10 (13%) | 2 (5%) | 6 (15%) | ||
| HER-2 | 0.775 | >0.999 | ||||
| Negative/Unknown | 46 (90%) | 70 (89%) | 37 (90%) | 36 (88%) | ||
| Positive | 5 (10%) | 9 (11%) | 4 (10%) | 5 (12%) | ||
| NLR | 0.021 | 0.822 | ||||
| ≤3 | 35 (69%) | 38 (48%) | 25 (61%) | 24 (59%) | ||
| >3 | 16 (31%) | 41 (52%) | 16 (39%) | 17 (41%) | ||
1N(%)
2Pearson's chi-squared test; Fisher's exact test