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. 2025 Jul 24;16(11):3415–3424. doi: 10.7150/jca.110306

Figure 1.

Figure 1

The causal relationship of PsO and SKCM by MR analysis. (A) Forest plot displaying the effect estimates of genetic variants associated with PsO on SKCM risk. Each line represents a SNP, with the red line indicating the overall effect estimate. (B) Scatter plot showing the relationship between the genetic associations with PsO and SKCM for each SNP. The regression lines represent different MR methods, including Inverse Variance Weighted, Weighted Median, MR-Egger, Weighted mode and Simple mode. (C) Forest plot representing the results of the MR leave-one-out sensitivity analysis for the effect of PsO on SKCM. (D) Forest plot displaying the effect estimates of genetic variants associated with SKCM on PsO risk. Each line represents a SNP, with the red line indicating the overall effect estimate.