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. 2025 Jul 24;16(11):3415–3424. doi: 10.7150/jca.110306

Figure 4.

Figure 4

The immune characterize of HLA-DOB in SKCM with single-cell RNA sequencing analysis. (A) UMAP plot illustrating the cell type distribution in SKCM, including B cells, endothelial cells, epithelial cells, fibroblasts, myeloid cells, NK cells, and T cells. (B) Feature plot of HLA-DOB expression in different cell types of SKCM. The color intensity represents the level of HLA-DOB expression. (C) UMAP plot illustrating the cell type distribution of B cell subsets in SKCM, including B_cells:Memory, B_cells:naive, and B_cells:plasma_cells. (D) Feature plot of HLA-DOB expression in different types of B cell subsets in SKCM. The color intensity represents the level of HLA-DOB expression. (E) UMAP plot illustrating the cell type distribution of myeloid cells subset in SKCM, including DC: monocyte-derived and Monocyte: CD16+. (F) Feature plot of HLA-DOB expression in different types of myeloid cell subsets in SKCM. The color intensity represents the level of HLA-DOB expression.