Table 3.
The univariate and multivariate analyses of OS
| Characteristics | Total(N) | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|---|
| Hazard ratio (95% CI) | P value | Hazard ratio (95% CI) | P value | ||
| Pathologic T stage | 237 | ||||
| T1&T2 | 169 | Reference | Reference | ||
| T3&T4 | 68 | 3.164 (2.004 - 4.993) |
< 0.001 | 2.146 (0.290 - 15.877) |
0.455 |
| Pathologic N stage | 237 | ||||
| N0 | 233 | Reference | |||
| N1 | 4 | 2.098 (0.513 - 8.584) |
0.303 | ||
| Pathologic M stage | 237 | ||||
| M0 | 233 | Reference | Reference | ||
| M1 | 4 | 3.972 (1.245 - 12.673) |
0.020 | 1.938 (0.592 - 6.340) |
0.274 |
| Pathologic stage | 237 | ||||
| Stage I&Stage II | 165 | Reference | Reference | ||
| Stage III&Stage IV | 72 | 3.144 (1.993 - 4.962) |
< 0.001 | 1.429 (0.194 - 10.542) |
0.726 |
| Gender | 237 | ||||
| Female | 74 | Reference | |||
| Male | 163 | 0.761 (0.476 - 1.217) |
0.255 | ||
| Age | 237 | ||||
| <= 60 | 131 | Reference | |||
| > 60 | 106 | 1.195 (0.758 - 1.883) |
0.443 | ||
| Histologic grade | 237 | ||||
| G1&G2 | 132 | Reference | |||
| G3&G4 | 105 | 1.034 (0.655 - 1.632) |
0.886 | ||
| HDAC7 | 237 | ||||
| Low | 115 | Reference | Reference | ||
| High | 122 | 1.915 (1.195 - 3.070) |
0.007 | 1.906 (1.181 - 3.075) |
0.008 |