Table 1.
Characteristics of the studied bank vole pools. The 12 pools of in total 32 bank voles studied for PFAS (per- and polyfluoroalkyl substances) and liver histopathology showing the sex (F female, M male), age (J juvenile, A adult), number of voles per pool (N), concentrations (ng/g ww) in liver of four PFAS that have been previously studied for toxic effects, and assessment (mean based on two independent assessments; range with a maximum of 1–5 (mild-severe) is given in parentheses) of observed cytoplasmatic changes. Liver sections for all 32 bank voles along with detailed descriptions of histopathological observations are given in supplementary table S5.
| Pool | Sex | Age | N | PFOA | PFNA | L-PFOS | PFHxS | Cytoplasmatic changes |
|---|---|---|---|---|---|---|---|---|
| 1 | F | J | 3 | 2.2 | 7.3 | 4430 | 285.7 | 1.8 (1–3) |
| 2 | F | J | 3 | 0.3 | 2.4 | 3086 | 71.4 | 3.2 (2–4) |
| 3 | F | J | 3 | 1.4 | 3.2 | 3073 | 68.8 | 3.5 (2–4) |
| 4 | F | A | 3 | 0.3 | 0.5 | 469 | 5.5 | 1.8 (1–3) |
| 5 | F | A | 2 | 1.1 | 10.4 | 10,749 | 252.0 | 2.0 (1–3) |
| 6 | M | J | 3 | 1.3 | 3.1 | 2736 | 125.4 | 2.5 (1–5) |
| 7 | M | J | 3 | 1.1 | 2.5 | 1371 | 7.2 | 2.5 (2–3) |
| 8 | M | J | 2 | 1.4 | 7.5 | 11,380 | 178.1 | 2.0 (2–2) |
| 9 | M | J | 2 | 0.8 | 3.6 | 8957 | 149.0 | 3.0 (2–4) |
| 10 | M | A | 3 | 0.3 | 0.5 | 2903 | 26.42 | 3.0 (1.5-5) |
| 11 | M | A | 3 | 0.8 | 1.4 | 1270 | 79.32 | 2.8 (1–5) |
| 12 | M | A | 2 | 1.4 | 0.5 | 1222 | 13.22 | 2.5 (1–4) |