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. 2025 Aug 23;15:31065. doi: 10.1038/s41598-025-17115-w

Table 3.

Alterations in corneal peripheral defocus, hoas, and TZ diameter in the corneal anterior surface pre- and post- ortho-k lens treatment (mean ± SD).

Time Corneal peripheral defocus (D) HOAs (µm) Horizontal coma (µm) Vertical coma (µm) Spherical aberration (µm) TZ diameter
0d NA 0.400 ± 0.185 0.024 ± 0.251 − 0.055 ± 0.242 0.196 ± 0.082 NA
1 m 7.53 ± 1.98 1.173 ± 0.345* 0.390 ± 0.486* − 0.048 ± 0.522 0.742 ± 0.200* 2.656 ± 0.465
6 m 7.69 ± 2.10 1.227 ± 0.393* 0.414 ± 0.549* 0.011 ± 0.600 0.730 ± 0.176* 2.851 ± 0.506
12 m 7.88 ± 2.17 1.238 ± 0.333* 0.451 ± 0.486* 0.004 ± 0.606 0.720 ± 0.177* 2.907 ± 0.477
F 0.653 150.874 17.515 0.402 245.457 6.933
P-value 0.521 0.000 0.000 0.751 0.000 0.001

HOAs higher-order aberrations, TZ treatment zone, NA no applicable.

*Indicates statistical difference from baseline.