Table 4.

Multivariate linear regression analyses of AL elongation and ocular parameters with ortho-k.

Parameter	Unadjusted model*			Adjusted model 1*			Adjusted model 2*
	Standardized beta	Beta (95% CI)	P-value	Standardized beta	Beta (95% CI)	P-value	Standardized beta	Beta (95% CI)	P-value
∆ Total aberration	0.085	0.012 (− 0.028 to 0.053)	0.552	0.211	0.019 (− 0.014 to 0.062)	0.167	0.192	0.027 (− 0.009 to 0.064)	0.142
∆ HOAs	− 0.366	− 0.260 (− 0.430 to − 0.090)	0.003	− 0.283	− 0.202 (− 0.360 to − 0.043)	0.013	− 0.331	− 0.236 (− 0.403 to − 0.068)	0.006
∆ horizontal coma	− 0.284	− 0.132 (− 0.210 to − 0.055)	0.001	− 0.262	− 0.122 (− 0.194 to − 0.051)	0.001	− 0.209	− 0.097 (− 0.171 to − 0.024)	0.010
corneal peripheral defocus	− 0.287	− 0.033 (− 0.056 to − 0.010)	0.006	− 0.364	− 0.042 (− 0.064 to − 0.020)	0.000	− 0.318	− 0.037 (− 0.058 to − 0.015)	0.001
TZ diameter	0.275	0.145 (0.048 to 0.243)	0.004	0.294	0.155 (0.066 to 0.245)	0.001	0.261	0.138 (0.050 to 0.226)	0.003

CI confidence interval, PD pupil diameter, AL axial length, HOAs higher-order aberrations, TZ treatment zone.

*In adjusted model 1, age and sex were adjusted; in adjusted model 2, PD, AL, and SE were adjusted based on model 1.