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. 2025 Aug 23;15:31065. doi: 10.1038/s41598-025-17115-w

Table 5.

Multivariate logistic regression analyses of AL elongation and ocular parameters with ortho-k.

Parameter Unadjusted model* Adjusted model 1* Adjusted model 2*
B OR (95% CI) P-value B OR (95% CI) P-value B OR (95% CI) P-value
∆ Total aberration 0.492 1.635 (0.767 to 3.487) 0.203 0.747 2.112 (0.909 to 4.905) 0.082 0.790 2.204 (0.873 to5.567) 0.094
∆ HOAs − 4.228 0.015 (0.001 to 0.420) 0.014 − 4.435 0.012 (0.000 to 0.530) 0.022 − 4.690 0.009 (0.000 to 0.730) 0.036
∆ horizontal coma − 2.469 0.085 (0.016 to 0.444) 0.004 − 2.634 0.072 (0.012 to0.428) 0.004 − 2.093 0.123 (0.018 to0.838) 0.032
corneal peripheral defocus − 0.533 0.587 (0.390 to 0.884) 0.011 − 0.789 0.454 (0.2814 to 0.734) 0.001 − 0.788 0.455 (0.270 to 0.766) 0.003
TZ diameter 2.075 7.966 (1.552 to 40.872) 0.013 2.807 16.560 (2.689 to 102.00) 0.002 2.499 12.172 (1.499 to 98.811) 0.019

CI confidence interval, PD pupil diameter, AL axial length, HOAs higher-order aberrations, TZ treatment zone, OR odd ratio.

* In adjusted model 1, age and sex were adjusted; in adjusted model 2, PD, AL, and SE were adjusted based on model 1.