Table 2.

Experimental groups and cohort allocation (male/female rats per group).

Treatment group	Behavioral tests(Open field, Marble burying, Hot plate, FST) (M/F)	Novel object recognition (NORT cohort) (M/F)	BDNF mRNA analysis (PCR cohort) (M/F)
Saline (Control)	7/7	7/7	3/3
Ketamine	7/7	7/7	3/3
Olanzapine	7/7	7/7	–a
Ketamine + Olanzapine	7/7	7/7	3/3

a No BDNF mRNA data were collected for the Olanzapine-only group (this group was not included in the PCR cohort; BDNF analysis was focused on Saline vs. Ketamine vs. Ket + Olanzapine, see text).

b Separate cohorts of animals were used for behavioral tests, NORT, and molecular analysis to prevent interference between tests. Each value in the table represents the number of Male/Female rats in that group’s cohort. Thus, each treatment group had a total of 17 rats per sex (7 + 7 + 3) across all cohorts.