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. 2025 Jun 28;17(2):74–79. doi: 10.34172/jcvtr.025.33085

Table 1. Major studies on Ischaemic mitral regurgitation .

Studies Year, Journal Participants Inference
Aklog et al3 2001, Circulation 136 Need for concomitant mitral intervention alongside CABG
Tolis et al4 2002, Ann Thorac Surg 183 Adequacy of isolated CABG for moderate IMR
Reece et al5 2009, J Thorac Cardiovasc Surg 110 Favourable outcomes with mitral repair over replacement
POINT Trial6 2009, J Thorac Cardiovasc Surg 102 Improved outcomes with concomitant mitral annuloplasty
RIME Trial7 2012, Circulation 73 Favourable outcomes with concomitant mitral annuloplasty
CTSN Trial8 2016, NEJM 251 Higher adverse events and regurgitation recurrence in mitral repair group
CTSN Trial 29 2016, NEJM 301 No added advantage in LV reverse remodelling with additional mitral valve repair in moderate MR