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. Author manuscript; available in PMC: 2025 Aug 25.
Published in final edited form as: J Acquir Immune Defic Syndr. 2025 Feb 1;98(2):123–132. doi: 10.1097/QAI.0000000000003543

TABLE 2.

Association Between Injection Drug Use and Select Demographic, Mental Health, Safety, and Discrimination Outcomes Among Transgender Women—NHBS-Trans, 7 US Cities, 2019–2020

Total Injected Drugs, Past 12 mo Adjusted Models*
N n Row% aPR (95% CI) P
Overall 1558 104 6.7
Race/ethnicity
 Hispanic/Latina§ 624 37 5.9 Ref
 Black/African American 547 35 6.4 1.40 (0.94 to 2.08) 0.098
 White 176 21 11.9 1.97 (1.34 to 1.40) <0.001
Gender identity
 Transgender woman 1001 60 6.0 Ref
 Woman 174 12 6.9 1.19 (0.77 to 1.85) 0.431
 Multiple genders listed 383 32 8.4 1.29 (0.92 to 1.82) 0.145
Age group (yr)
 18–29 483 27 5.6 Ref
 30–39 446 37 8.3 1.43 (0.74 to 2.74) 0.288
 40–49 293 18 6.1 0.95 (0.51 to 1.74) 0.859
 ≥50 336 22 6.6 0.95 (0.53 to 1.69) 0.851
Education
 Less than high school 335 25 7.5 Ref
 High school or equivalent 573 48 8.4 1.19 (0.67 to 2.12) 0.560
 Some college or more 648 31 4.8 0.63 (0.35 to 1.15) 0.134
Currently insured
 No 262 12 4.6 Ref
 Yes 1295 92 7.1 1.56 (0.76 to 3.17) 0.223
Saw a health care provider, past 12 mo
 No 100 5 5.0 Ref
 Yes 1458 99 6.8 1.37 (0.66 to 2.82) 0.397
Poverty level, past 12 mo
 Above poverty level 567 33 5.8 Ref
 Below poverty level 977 71 7.3 1.25 (0.84 to 1.87) 0.270
Food insecurity, past 12 mo
 No 646 22 3.4 Ref
 Yes 909 82 9.0 2.45 (1.50 to 4.01) <0.001
Has a disability
 No 725 30 4.1 Ref
 Yes 825 73 8.9 1.85 (1.18 to 2.89) 0.007
Currently homeless
 No 1201 49 4.1 Ref
 Yes 356 55 15.5 3.59 (2.54 to 5.07) <0.001
Incarcerated, past 12 mo
 No 1285 62 4.8 Ref
 Yes 270 41 15.2 3.21 (2.32 to 4.44) <0.001
Social support
 Low/moderate 848 45 5.3 Ref
 High 706 58 8.2 1.35 (0.84 to 2.15) 0.214
Noninjection drug use
 No 628 19 3.0 Ref
 Yes 929 85 9.2 3.07 (1.97 to 4.79) <0.001
Mental health and safety outcomes
 Psychological distress, past 30 d
  No 1151 66 5.7 Ref
  Yes 403 38 9.4 1.57 (1.06 to 2.32) 0.024
 Verbally abused or harassed, past 12 mo
  No 710 30 4.2 Ref
  Yes 846 74 8.8 1.96 (1.36 to 2.81) <0.001
 Physical violence (including intimate partner violence), past 12 mo
  No 1045 51 4.9 Ref
  Yes 512 53 10.4 2.04 (1.51 to 2.76) <0.001
 Forced sex, past 12 mo
  No 1321 73 5.5 Ref
  Yes 233 31 13.3 2.30 (1.62 to 3.29) <0.001
 Received money or drugs for sex, past 12 mo
  No 1024 39 3.8 Ref
  Yes 534 65 12.2 3.23 (2.47 to 4.23) <0.001
Discrimination because of gender identity or presentation
 Trouble getting a job, past 12 mo
  No 1032 61 5.9 Ref
  Yes 504 42 8.3 1.37 (0.96 to 1.98) 0.085
 Denied access to appropriate bathroom, past 12 mo
  No 1203 70 5.8 Ref
  Yes 348 34 9.8 1.68 (1.22 to 2.30) 0.001
 Denied housing or evicted, past 12 mo
  No 1333 75 5.6 Ref
  Yes 217 28 12.9 2.16 (1.65 to 2.82) <0.001
 Denied health care, past 12 mo
  No 1377 86 6.3 Ref
  Yes 169 17 10.1 1.49 (0.95 to 2.31) 0.079
 Received poorer services, past 12 mo
  No 942 44 4.7 Ref
  Yes 608 59 9.7 2.06 (1.46 to 2.90) <0.001
*

Models adjusted for network size and MSA.

N’s do not include missing values.

The other race/ethnicity categories were too small to report.

§

Hispanic/Latina can be of any race.