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. Author manuscript; available in PMC: 2025 Aug 25.
Published in final edited form as: Toxicology. 2025 Jan 31;512:154068. doi: 10.1016/j.tox.2025.154068

Fig. 3.

Fig. 3.

Transcriptomic profile of CBD-treated mouse Sertoli TM4 cells. (A) Number of DEGs in mouse Sertoli TM4 cells treated with 10 – 20 μM CBD for 24 h. Blue bars indicate the number of down-regulated genes and red bars represent the number of up-regulated genes. (B) Venn diagrams show the number of DEGs from CBD-treated mouse Sertoli TM4 cells. Numbers in each section represent the numbers of DEGs at different CBD concentrations. Venn diagrams were created using InteractiVenn: http://www.interactivenn.net/. The dark orange-colored center area in the Venn diagrams denotes the number of overlapped DEGs across all concentrations tested. (C) Heatmap showing the changes of expression level of 23 common genes in mouse Sertoli TM4 cells upon treated with 10 – 20 μM CBD.