Study period
	Pre-screen	Treatment	Post-allocation
Timepoint (day)	− 7 ~ 0	0	1	2	3	10 ± 3	30 ± 3
Enrolment	Screening/baseline	Operation day	POD1 ward run	POD2 ward run	POD3 ward run	OPD visit	Final study visit
Clinical visit/inform consent	X
Inclusion/exclusion criteria	X
Medical and surgical history and demographics	X
Physical exam	X
High and body weight	X
Laboratory data	X
Interventions
Randomization/administration	X
Surgery		X
Peritoneal fluid analysis		X
Assessments
Vital signs		X	X	X	X
Morbidity/mortality		X	X	X	X	X	X
Postoperative recovery		X	X	X	X
The length of hospital stays		X	X	X	X
Inflammatory and immune markers			X		X
Pathology report						X