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. 2025 Aug 25;78:17. doi: 10.1186/s13620-025-00306-2

Table 1.

Sensitivity profiles of E. coli strains to antimicrobial agents of different antibiotic classes

Class of antibiotics Antibiotic Average of zone of inhibition
(range) [mm]
Results of susceptibility*
(No.**)
n = 97
R I S
Penicillins ampicillin (AM) 20.8 (17–29) 0 0 97
ampicillin-sulbactam (SAM) 23.6 (20–34) 0 0 97
amoxicillin-clavulanic acid (AMC) 22.4 (18–26) 3 0 94
piperacillin (PRL) 28.4 (17–33) 1 0 96
piperacillin-tazobactam (TPZ) 28.1 (21–32) 0 0 97
ticarcillin-clavulanic acid (TTC) 28.6 (22–31) 0 1 96
Cephalosporins ceftazidime (CAZ) 28.1 (23–31) 0 0 97
cefuroxime (CXM) 24.9 (20–28) 0 97 0
Carbapenems imipenem (IMP) 21.3 (12–25) 9 34 54
meropenem (MEM) 32.0 (24–36) 0 0 97
Monobactams aztreonam (ATM) 30.8 (25–35) 2 0 95
Fluoroquinolones nalidixic acid (NA)a 36.4 (16–38) 0 4 93
ofloxacin (OFX) 30.8 (20–35) 3 3 91
Aminoglycosides kanamycin (K)a 22.5 (20–26) 0 0 97
streptomycin (S)a 14.9 (13–20) 0 38 59
Macrolides, lincosamides and streptogramins azithromycin (AZM) 24.4 (13–30) 0 0 97
Tetracyclines doxycycline (DO)a 19.9 (10–26) 5 2 90
tetracycline (TE)a 23.9 (0–28) 7 0 90
Miscellaneous agents chloramphenicol (C) 29.1 (22–34) 0 0 97
trimethoprim-sulfamethoxazole (TS) 32.0 (28–35) 0 0 97

*R- Resistant, I- Intermediate sensitive, increased exposure, S-Susceptible, standard dosing regimen; **No.- numer of strains

a interpretation of the CLSI breakpoints (CLSI Version 1.0, updated 15 May 2023)