Table 2.

MIC₅₀, MIC₉₀ of tested C. difficile strains.

Antibiotic	MIC50	MIC90	Strains resistant		Breakpoints used [mg/L]
			n = 130	%
Metronidazolea	1	2	5	4	S ≤ 2, R > 2
Vancomycina	0.38	0.5	0	0	S ≤ 2, R > 2
Erythromycinb	256	256	87	67	R > 256
Clindamycind	8	256	128	98	S ≤ 0.25, R > 0.25
Moxifloxacinc	32	32	130	100	4
Rifampicinc	32	32	83	64	0.004
Piperacillin/Tazobactamd	3	6	129	99	S ≤ 0.5, R > 0.5
Imipenemd	32	32	129	99	S ≤ 0.5, R > 0.5
Benzylpenicillind	1	2	108	83	S ≤ 0.5, R > 0.5
Chloramphenicole	6	12	17	13	S ≤ 8, R > 8

^aResistance according to EUCAST (v.15 2024).

^bAssumed R > 256 mg/L.

^cECOFF for C. difficile was used.

^dMICs for C. perfringens according to EUCAST 2024.

^eMICs for Gram-positive anaerobes were used because lack of them according EUCAST (v.11).