Fig. 3.

F1 score for the benchmark of calling ADO and LDO. Varying are the mutation rate (the horizontal axis), the relative deletion rate (the vertical strip), the coverage quality (the horizontal strip), and the simulated ADO type (the shaded or blank boxes). Each simulation is repeated $n=10$ times, with each repetition denoted by colored dots. The gray dashed lines represent the optimal values of each metric. Box plots comprise medians, boxes covering the interquartile range (IQR), and whiskers extending to 1.5 times the IQR below and above the box. Both DelSIEVE and SIEVE were configured to match the dropout mode (ADO or LDO) employed during the simulation process. Box plots of the F1 score for calling ADO (a) and LDO (b). The F1 scores were unavailable in b when data was of low coverage quality due to unavailable precision. The results of calling LDO for data simulated with ADO are not available in b, as both models were configured for the same dropout mode as used in the simulated data and were not able to call LDO in this case