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. 2025 Aug 25;83:217. doi: 10.1186/s13690-025-01703-3

Table 2.

Association between polypharmacy and clinical outcomes in older adults: multivariable logistic regression

Sample Odds Ratio (OR) (95% Confidence Interval)
Hospitalization Mortality
Total (n = 3,297) 1.52(1.28–1.81) * 3.17(1.19–8.44) *
65–79 years old (n = 2,861) 1.48(1.23–1.79) * 3.72(1.06–13.05) *
≥ 80 years old (n = 436) 1.78(1.06–2.99) * 1.90(0.37–9.68)
Males (n = 1,488) 1.68(1.30–2.17) * 2.91(0.80–10.59)
Females (n = 1,809) 1.40(1.10–1.79) * 3.23(0.70–14.94)
Living alone (n = 707) 1.05(0.72–1.53) 1.92(0.33–11.12)
Not living alone (n = 2,590) 1.69(1.38–2.06) * 4.08(1.18–14.12) *

Notes. Models controlling for age (years), sex, residential areas, income quartile (household), health insurance type, having private medical insurance, health screening in 2 years, cancer screening in 2 years, education level, Charlson comorbidity index, disability, BMI, living alone, walking days per week, having ever smoked, non-excessive drink, and calendar year. *p < 0.05