Table 5.
Frontal Time-Frequency results: between PMS and TD
| Variable | Delta (µV2) | Theta (µV2) | Alpha (µV2) | Beta (µV2) | Gamma (µV2) | Beta-gamma (ITC) | Alpha-Beta (ITC) | Delta-Theta (ITC) |
|---|---|---|---|---|---|---|---|---|
| Group | −0.048 | 0.066 | −0.259 | 0.472 | *−0.028 | *−0.038 | ||
| Stim | ***−0.064 | |||||||
| Age | *−0.046 | ~−0.039 | −0.031 | −0.004 | 0.010 | *−0.001 | ||
| Sex | 0.279 | 0.174 | 0.366 | −1.162 | **−2.715 | ***−0.041 | **−0.049 | |
| Trials | −0.013 | −0.015 | −0.010 | −0.009 | 0.001 | |||
| System | 0.428 | 0.840 | 0.738 | 0.090 | *1.801 | |||
| Age*Group | **0.055 | *0.050 | **0.063 | ~ 0.041 | **0.001 | |||
| Age*System | *−0.055 | *−0.076 | *−0.075 | ***−0.140 | ***−0.106 | |||
| Age*Trials | ||||||||
| Sex*Group | **−3.704 | *−3.645 | **−4.390 | **−4.423 | ||||
| Sex*System | **3.808 | *3.633 | 1.429 | ~ 2.615 | ||||
| Sex*Trials | −0.000 | |||||||
| Group*System | 1.839 | 2.043 | *4.320 | ~ 3.176 | ||||
| Group*Trials | **−0.084 | *−0.083 | *−0.078 | **−0.084 | ||||
| System*Trials | *0.104 | ~ 0.083 | ~ 0.085 | |||||
| Omnibus F | F(12, 61) = 11.6 | F(12, 61) = 9.11 | F(12, 61) = 8.34 | F(11, 62) = 9.23 | F(4, 69) = 9.40 | F(6, 67) = 6.88 | F(3, 70) = 8.84 | F(1, 73) = 105 |
| Model p-value | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 |
| Mean | 52.4 | 51.2 | 47.5 | 39.9 | 24.8 | 0.046 | 0.093 | 0.126 |
| 0.695 | 0.642 | 0.621 | 0.621 | 0.353 | 0.381 | 0.275 | 0.000 | |
| Univariable: Stim 1 | −1.7 (−4.3, 0.1) | −1.1 (−4.0, 1.4) | −1.1 (−3.3, 1.1) | −0.1 (−2.1, 2.0) | −0.2 (−3.1, 2.3) | *−0.0 (−0.1, −0.0) | ~−0.1 (−0.1, 0.0) | −0.0 (−0.1, 0.0) |
| Univariable: Stim 2 | −1.7 (−4.0, 0.4) | −1.3 (−4.0, 1.1) | −1.0 (−3.5, 1.2) | 0.0 (−2.1, 2.2) | −0.5 (−3.1, 2.3) | −0.0 (−0.1, 0.0) | 0.0 (−0.0, 0.0) | −0.0 (−0.1, 0.1) |
Note: Table of parameter estimates. Each column represents a group LASSO model of an EEG outcome variable. Parameter estimates less than 0.001 were shortened to 0.000 to save space. ~p <.10, *p <.05, **p <.01, ***p <.001. Variables with no symbol were retained by group LASSO but not significant in the final model. A non-significant model means that independent variables did not improve model fit over an intercept-only model. Only variables chosen by group LASSO are presented. Reference groups are as follows—Stimulus: Stimulus 1, Sex: Male, Group: TD, System: EGI. ITC, intertrial phase coherence; Stim, stimulus; TD, typically developing; PMS, Phelan McDermid Syndrome. The univariable rows indicate the median difference and 95% confidence interval between PMS and TD for each EEG outcome variable to either the first or second auditory stimulus (for additional details on the univariable analyses, see Supplemental Table 2). For these univariable results, negative values are lower for PMS vs. TD, and positive values are higher for PMS vs. TD. The bold highlights potentially clinically relevant cells in which p <.25. ~p <.10, *p <.05, **p <.01, ***p <.001