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. 2025 Aug 25;24:348. doi: 10.1186/s12933-025-02905-3

Table 2.

Risk of incident atrial fibrillation in young adults with SLD

Subgroup Number Number of events Follow-up duration
(p-y)
Incidence rate
(per 1,000 p-y)
Crude HR
(95% CI)
Adjusted HR (95% CI)
Model 1* Model 2*
Non-SLD 4,603,095 14,772 47,427,013 0.31 1.00 (Reference) 1.00 (Reference) 1.00 (Reference)
All SLD 1,772,615 11,620 18,387,460 0.63 2.02 (1.97 –2.07) 1.49 (1.45 –1.53) 1.14 (1.10– 1.18)
MASLD 1,448,817 9,014 15,032,918 0.60 1.92 (1.87–1.97) 1.41 (1.37–1.45) 1.09 (1.05–1.31)
MetALD 239,830 1,834 2,486,934 0.74 2.36 (2.24–2.47) 1.73 (1.64–1.81) 1.29 (1.22–1.36)
ALD 83,968 772 867,609 0.89 2.85 (2.65–3.06) 2.08 (1.93–2.24) 1.52 (1.41–1.65)

* Model 1 adjusted by age and sex; Model 2 adjusted by age, sex, low income status, smoking, regular exercise, total cholesterol, fasting blood glucose level, systolic blood pressure, estimated glomerular filtration rate, and body mass index

ALD, alcohol-associated liver disease; CI, confidence interval; ; HR, hazard ratio; MASLD, metabolic dysfunction-associated steatotic liver disease; MetALD, metabolic dysfunction and alcohol-related liver disease; p-y, person-years; SLD, steatotic liver disease