Table 2.
Risk of incident atrial fibrillation in young adults with SLD
| Subgroup | Number | Number of events | Follow-up duration (p-y) |
Incidence rate (per 1,000 p-y) |
Crude HR (95% CI) |
Adjusted HR (95% CI) | |
|---|---|---|---|---|---|---|---|
| Model 1* | Model 2* | ||||||
| Non-SLD | 4,603,095 | 14,772 | 47,427,013 | 0.31 | 1.00 (Reference) | 1.00 (Reference) | 1.00 (Reference) |
| All SLD | 1,772,615 | 11,620 | 18,387,460 | 0.63 | 2.02 (1.97 –2.07) | 1.49 (1.45 –1.53) | 1.14 (1.10– 1.18) |
| MASLD | 1,448,817 | 9,014 | 15,032,918 | 0.60 | 1.92 (1.87–1.97) | 1.41 (1.37–1.45) | 1.09 (1.05–1.31) |
| MetALD | 239,830 | 1,834 | 2,486,934 | 0.74 | 2.36 (2.24–2.47) | 1.73 (1.64–1.81) | 1.29 (1.22–1.36) |
| ALD | 83,968 | 772 | 867,609 | 0.89 | 2.85 (2.65–3.06) | 2.08 (1.93–2.24) | 1.52 (1.41–1.65) |
* Model 1 adjusted by age and sex; Model 2 adjusted by age, sex, low income status, smoking, regular exercise, total cholesterol, fasting blood glucose level, systolic blood pressure, estimated glomerular filtration rate, and body mass index
ALD, alcohol-associated liver disease; CI, confidence interval; ; HR, hazard ratio; MASLD, metabolic dysfunction-associated steatotic liver disease; MetALD, metabolic dysfunction and alcohol-related liver disease; p-y, person-years; SLD, steatotic liver disease