Table 2.
Comparative outcomes between narrow-bore and standard extension tubes: primary analysis and propensity-matched sensitivity evaluation
| Outcome | Primary | p-value2 | PSM adjusted | p-value2 | ||
|---|---|---|---|---|---|---|
| Standard, n = 1371 | Narrow, n = 1371 | Standard, n = 1201 | Narrow, n = 1201 | |||
| Hypoxemia | 37 (27.0%) | 16 (11.7%) | 0.001 | 28 (23.3%) | 13 (10.8%) | 0.010 |
| Severe hypoxemia | 27 (19.7%) | 10 (7.3%) | 0.003 | 19 (15.8%) | 8 (6.7%) | 0.025 |
| Time to achieve deep sedation (s) | 54.0 (46.0, 65.0) | 70.0 (63.0, 81.0) | < 0.001 | 54.0 (45.0, 65.0) | 70.0 (62.0, 80.0) | < 0.001 |
| Induction dose of propofol (mg) | 150.0 (150.0, 175.0) | 150.0 (140.0, 160.0) | 0.012 | 150.0 (150.0, 175.0) | 150.0 (138.0, 160.0) | 0.040 |
| Total dose of propofol (mg) | 200.0 (200.0, 250.0) | 200.0 (150.0, 210.0) | < 0.001 | 200.0 (180.0, 250.0) | 190 (150.0, 203.0) | < 0.001 |
| POPI | 20 (14.6%) | 27 (19.7%) | 0.262 | 19 (15.8%) | 24 (20.0%) | 0.400 |
| Lowest SpO2 (%) | 96 (89, 98) | 97 (93, 99) | 0.007 | 96 (91, 98) | 97 (93, 99) | 0.049 |
| Airway interventions | 0.039 | 0.076 | ||||
| Jaw lift | 20 (54.1%) | 3 (18.8%) | 17 (60.7%) | 3 (23.1%) | ||
| Modified Manual Chest Compression | 5 (13.5%) | 6 (37.5%) | 4 (14.3%) | 5 (38.5%) | ||
| Mask ventilation | 12 (32.4%) | 7 (43.8%) | 7 (25.0%) | 5 (38.5%) | ||
| Procedure duration (min) | 6. 1 (5.1, 8.2) | 5.7 (4.3, 7.4) | 0.156 | 6.1 (5.0, 8.2) | 5.6 (4.3, 7.4) | 0.188 |
POPI pain on propofol injection
1n (%); Median (IQR)
2Pearson’s Chi-squared test; Wilcoxon rank sum test; Fisher’s exact test