Table 3.
Association between 5-year changes in AIP and 10-year risk of T2DM
| 5-year Changes in AIP | Cases/N | HRs (95% CIs) | ||||||
|---|---|---|---|---|---|---|---|---|
| Model 1a | Model 2b | Model 3c | Model 4d | |||||
| Decrease | 279/2217 | 0.74 (0.63–0.86) | 0.73 (0.63–0.86) | 0.75 (0.63–0.89) | 0.80 (0.67–0.95) | |||
| Stable | 528/4434 | 1.00 (Reference) | 1.00 (Reference) | 1.00 (Reference) | 1.00 (Reference) | |||
| Increase | 265/2217 | 1.18 (1.02–1.38) | 1.20 (1.03–1.39) | 1.26 (1.06–1.48) | 1.18 (1.00-1.40) | |||
| Per SD | 1.24 (1.16–1.32) | 1.25 (1.17–1.33) | 1.24 (1.16–1.34) | 1.20 (1.11–1.29) | ||||
| p for trend | < 0.0001 | < 0.0001 | < 0.0001 | < 0.0001 | ||||
a Unadjusted model
b Adjusted for age and gender
c Adjusted for variables in model 2 as well as marital status, education level, monthly individual income, smoking status, alcohol drinking, physical activity, and family history of T2DM
d Adjusted for variables in model 3 as well as bmi, systolic blood pressure and total cholesterol