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. Author manuscript; available in PMC: 2025 Aug 25.
Published in final edited form as: Nat Methods. 2024 Nov 8;22(1):24–40. doi: 10.1038/s41592-024-02480-7

Figure 2.

Figure 2.

Variability in hiPSC-CM platforms. a. Top types of substrate platforms that hiPSC-CMs are seeded on in 2D. Multielectrode array (MEA). b. Top extracellular matrix (ECM) or biomaterial platform used to engineer cardiac microtissues. Polyethylene glycol (PEG). c. Fraction of cardiac microtissues that are composed of hiPSC-CMs alone (CM), hiPSC-CMs with mesenchymal stromal cells (CM + SC), or hiPSC-CMs with endothelial cells and mesenchymal stromal cells (CM + EC + SC). d. Left: Distribution of CM and SC composition in CM-SC cardiac microtissues (n = 50). Right: Distribution of CM, EC, and SC composition in CM-EC-SC cardiac microtissues (n = 26). Dashed and dotted lines represent medians and quartiles, respectively.