Figure 5.

Quantification of hiPSC-CM functionality and maturation. a-d. Average reported sarcomere length, contractile stress, conduction velocity (CV), and resting membrane potential (RMP) in hiPSC-CMs each year from 2016–2021 (n = 4–11). 2015 and 2022 were excluded from these graphs due to limited data availability (analysis was performed mid-2022). Red regions represent values benchmarked in adult human CMs. e-h. Average reported metrics based on types of maturation techniques that were used from all analyzed publications (n = 2–34). i-l. Average reported metrics based on the number of maturation techniques that were used from all analyzed publications (n = 2–20). Maturation techniques were classified as described in Figure 3. Error bars are standard error of the mean (SEM).