TABLE 1.
Characteristics of colorectal cancer patients at diagnosis (stratified by stage and type of cancer) and the general Dutch population, matched on sex and a 5-yr age range.
| Patients | General Population | ||||
|---|---|---|---|---|---|
| Total | St. I-III CC | St. I-III RC | St. IV CRC | Total | |
| (N = 4910) | (n = 2905) | (n = 1459) | (n = 436) | (n = 4910) | |
| Sex | |||||
| Male | 3111 (63%) | 1716 (59%) | 1029 (71%) | 288 (66%) | 3111 (63%) |
| Female | 1799 (37%) | 1189 (41%) | 430 (29%) | 148 (34%) | 1799 (37%) |
| Age | |||||
| Median (IQR) | 66.0 (59.1, 73.0) | 67.0 (61.0, 73.0) | 65.0 (58.0, 72.0) | 64.5 (57.0, 71.0) | 66.0 (59.0, 73.0) |
| MVPA-SL | |||||
| Median (IQR) | 5.0 (1.5, 10.5) | 5.0 (1.5, 10.0) | 5.0 (2.0, 11.0) | 4.3 (1.0, 9.8) | 6.0 (1.5, 12.5) |
| Missing | 220 (4.5%) | 117 (4.0%) | 54 (3.7%) | 25 (5.7%) | 0 (0%) |
| ACSM PA guideline adherence | |||||
| No | 2866 (61%) | 1724 (62%) | 819 (58%) | 266 (65%) | 2737 (56%) |
| Yes | 1824 (39%) | 1064 (38%) | 586 (42%) | 145 (35%) | 2173 (44%) |
| Missing | 220 (4.5%) | 117 (4.0%) | 54 (3.7%) | 25 (5.7%) | 0 (0%) |
| BMI | |||||
| Median (IQR) | 26.0 (23.8, 28.7) | 26.2 (23.8, 29.0) | 25.9 (24.0, 28.7) | 25.3 (23.2, 28.1) | 25.9 (23.7, 28.7) |
| Missing | 110 (2.2%) | 58 (2.0%) | 25 (1.7%) | 6 (1.4%) | 0 (0%) |
| Educational attainmenta | |||||
| Low | 1676 (36%) | 1040 (37%) | 471 (33%) | 132 (32%) | 1811 (37%) |
| Intermediate | 1372 (29%) | 804 (29%) | 418 (30%) | 123 (30%) | 1810 (37%) |
| High | 1661 (35%) | 953 (34%) | 521 (37%) | 159 (38%) | 1289 (26%) |
| Missing | 201 (4.1%) | 108 (3.7%) | 49 (3.4%) | 22 (5.0%) | 0 (0%) |
| Heavy drinkerb | |||||
| No | 4261 (91%) | 2522 (91%) | 1275 (91%) | 390 (95%) | 4449 (91%) |
| Yes | 418 (9%) | 252 (9%) | 133 (9%) | 21 (5%) | 461 (9%) |
| Missing | 231 (4.7%) | 131 (4.5%) | 51 (3.5%) | 25 (5.7%) | 0 (0%) |
| Smoking status | |||||
| Current | 387 (8%) | 204 (7%) | 140 (10%) | 38 (9%) | 863 (18%) |
| Former | 2772 (59%) | 1658 (59%) | 825 (58%) | 231 (56%) | 2469 (50%) |
| Never | 1568 (33%) | 946 (34%) | 454 (32%) | 144 (35%) | 1578 (32%) |
| Missing | 183 (3.7%) | 97 (3.3%) | 40 (2.7%) | 23 (5.3%) | 0 (0%) |
| Marital status | |||||
| Married/common law | 3888 (82%) | 2288 (81%) | 1181 (83%) | 344 (83%) | — |
| Single (includes single with kids) | 843 (18%) | 522 (19%) | 238 (17%) | 71 (17%) | — |
| Missing | 179 (3.6%) | 95 (3.3%) | 40 (2.7%) | 21 (4.8%) | — |
| Surgical resection | |||||
| No | 253 (5%) | 6 (<0.1%) | 98 (7%) | 148 (35%) | — |
| Yes | 4562 (95%) | 2899 (100%) | 1360 (93%) | 274 (65%) | — |
| Missing | 95 (1.9%) | 0 (0%) | 1 (0.1%) | 14 (3.2%) | — |
| Stoma | |||||
| No | 3637 (76%) | 2720 (95%) | 610 (42%) | 284 (68%) | — |
| Yes | 1128 (24%) | 157 (5%) | 835 (58%) | 132 (32%) | — |
| Missing | 145 (3.0%) | 28 (1.0%) | 14 (1.0%) | 20 (4.6%) | — |
| Systemic therapy (any)c | |||||
| No | 3062 (64%) | 1921 (67%) | 987 (68%) | 128 (30%) | — |
| Yes | 1737 (36%) | 967 (33%) | 467 (32%) | 301 (70%) | — |
| Missing | 111 (2.3%) | 17 (0.6%) | 5 (0.3%) | 7 (1.6%) | — |
| Radiotherapy (any) | — | ||||
| No | 3787 (80%) | 2833 (99%) | 610 (42%) | 317 (74%) | — |
| Yes | 958 (20%) | 16 (1%) | 831 (58%) | 110 (26%) | — |
| Missing | 165 (3.4%) | 56 (1.9%) | 18 (1.2%) | 9 (2.1%) | — |
| Fatigue scored | — | ||||
| Median (IQR) | 22 (0, 33) | 22 (0, 33) | 11 (0, 33) | 33 (11, 44) | — |
| Missing | 234 (4.8%) | 132 (4.5%) | 43 (2.9%) | 25 (5.7%) | — |
| Emotional functioning scored | — | ||||
| Median (IQR) | 83 (667, 100) | 83 (67, 100) | 83 (67, 92) | 83.3 (67, 92) | — |
| Missing | 218 (4.4%) | 117 (4.0%) | 42 (2.9%) | 25 (5.7%) | — |
Missing percentages are presented as percentages from the total sample, but are not included in the non-missing counts.
alow education: elementary and lower vocational education, intermediate: secondary education, high: higher vocational and university education.
bHeavy drinking: more than 14 units per week for females and more than 21 units per week for males.
cIncludes any chemotherapy administered, i.e. (neo-)adjuvant, in the context of chemoradiotherapy and palliative chemotherapy.
dSubscale of the EORTC core quality of life questionnaire (EORTC QLQ-C30.
Abbreviations:; St. I-III CC, stage I-III colon cancer; St. I-III RC, stage I-III rectal cancer; st. IV CRC, stage IV colorectal cancer; IQR, interquartile range; ACSM, American College of Sports Medicine; PA, physical activity; MVPA-SL, sport and leisure time moderate and vigorous physical activity; U, unit; M; male, F, female; BMI, body mass index.