. 2025 Aug 20;15(36):29377–29388. doi: 10.1039/d5ra03958d

Table 2. MIC values obtained from checkerboard assay of ciprofloxacin in combination with (a) pentagalloyl glucose (PGG) and (b) piperine performed for S. aureus (ATCC 700698).

Combination	MIC^alone (μg ml⁻¹)	MIC^comb (μg ml⁻¹)	FIC (MIC^comb/MIC^alone)	FICI	Effect
Ciprofloxacin	125	25	0.2	0.45	Synergy
PGG	250	62.5	0.25	0.45	Synergy
Ciprofloxacin	125	25	0.2	0.7	Additive
Piperine	250	125	0.5	0.7	Additive