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. Author manuscript; available in PMC: 2025 Aug 25.
Published in final edited form as: J Clin Psychiatry. 2025 Jan 29;86(1):24m15399. doi: 10.4088/JCP.24m15399

Table 3.

Treatment Outcome of First ECT Course

Characteristic Nonpsychotic depression
(N = 427)a
Psychotic depression
(N = 115)a
P valueb
CGI improvement from baseline
1—Very much improved 114 (27%) 47 (41%) .003
2—Much improved 208 (49%) 44 (38%) .046
3—Minimally Improved 71 (17%) 16 (14%) .5
4—No improvement or worse 34 (8.0%) 8 (7.0%) .7
CGI cognitive impairment rating
1—No impairment present 146 (34%) 37 (32%) .7
2—Impairment present but not functionally impairing 191 (45%) 50 (43%) .8
3—Impairment present and functionally impairing 74 (17%) 23 (20%) .5
4—Impairment present and outweighs therapeutic benefit 16 (3.7%) 5 (4.3%) .8
a

n (%).

b

Pearson χ2 test, Fisher exact test.

Abbreviations: CGI = Clinical Global Impression, ECT = electroconvulsive therapy.